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Translational Medicine / 转化医学Proteostasis, Proteasome Biology

Alfred Goldberg

PhD

🏢Harvard Medical School🌐USA

Professor of Cell Biology

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Key Contributions

👥Biography 个人简介

Alfred Goldberg pioneered the discovery of intracellular protein degradation pathways and the ubiquitin-proteasome system. His work enabled bortezomib and the proteasome inhibitor class for multiple myeloma. He remains a foundational figure in proteostasis biology.

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🧪Research Fields 研究领域

ubiquitin-proteasome system
proteasome inhibitors
protein degradation
myeloma therapy
proteostasis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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