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Translational Medicine / 转化医学Leukemia, FLT3 Inhibitors AML

Alexander Perl

MD, MS

🏢University of Pennsylvania🌐USA

Associate Professor of Medicine

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👥Biography 个人简介

Alexander Perl led the ADMIRAL trial establishing gilteritinib as a standard treatment for relapsed/refractory FLT3-mutated AML. His research has clarified mechanisms of FLT3 inhibitor resistance and identified strategies to overcome acquired resistance. He has contributed to the understanding of how to optimally integrate FLT3 inhibitors with chemotherapy and transplant approaches in AML.

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🧪Research Fields 研究领域

FLT3 inhibitors AML
gilteritinib ADMIRAL
midostaurin AML
FLT3-ITD resistance
quizartinib AML

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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