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Translational Medicine / 转化医学Tumor-Agnostic Approvals

Alexander Drilon

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Chief of Early Drug Development Service

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Key Contributions

👥Biography 个人简介

Alexander Drilon led pivotal trials of larotrectinib, entrectinib, selpercatinib, and repotrectinib across fusion-driven cancers, contributing to multiple tumor-agnostic FDA approvals in NTRK, RET, and ROS1 altered tumors. His work established fusion detection and targeting as a central axis of tumor-agnostic precision oncology. He continues to lead rare fusion drug development.

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🧪Research Fields 研究领域

larotrectinib entrectinib NTRK
selpercatinib RET tumor-agnostic
repotrectinib ROS1/NTRK
fusion-driven cancers
rare fusion drug development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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