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Translational Medicine / 转化医学Kinase Fusions, TRK/RET Inhibitors

Alexander Drilon

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Chief of Early Drug Development Service

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Key Contributions

👥Biography 个人简介

Alexander Drilon is a leading expert in TRK and RET fusion-driven cancers at Memorial Sloan Kettering. He has been instrumental in developing larotrectinib and entrectinib for NTRK fusions and selpercatinib for RET fusions. His research established tumor-agnostic approval pathways for kinase inhibitors. He leads early-phase clinical trials targeting oncogenic fusions across tumor types.

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🧪Research Fields 研究领域

RET fusions NSCLC
NTRK fusions pan-tumor
tumor-agnostic therapy
early drug development
kinase inhibitors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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