Alex Bhatt
MD
Associate Professor of Breast Oncology and Pharmacogenomics
👥Biography 个人简介
Alex Bhatt investigates the impact of CYP2D6 genetic variation on tamoxifen metabolism and breast cancer outcomes. His research has characterized how CYP2D6 poor metabolizer status reduces conversion of tamoxifen to its active metabolite endoxifen, potentially compromising breast cancer treatment. He has evaluated endoxifen-based dosing strategies to achieve therapeutic plasma levels regardless of CYP2D6 genotype. His clinical research has addressed the controversial question of whether CYP2D6 testing should guide tamoxifen dosing decisions in breast cancer patients.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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