Alberto Mantovani

Alberto Mantovani at Humanitas Research Hospital is a world authority on innate immunity and tumor-associated macrophages (TAMs). His foundational work characterizing the M1/M2 macrophage polarization paradigm and demonstrating that M2-like TAMs promote tumor progression through growth factor release, angiogenesis support, and immune suppression has shaped understanding of the tumor microenvironment. His extensive research on cancer-related inflammation has influenced both basic biology and therapeutic strategy.