Albert Koong
艾伯特·孔
MD, PhD
Professor and Chair of Radiation Oncology放射肿瘤学教授兼主任
👥Biography 个人简介
Albert Koong is an internationally recognized leader in pancreatic cancer stereotactic body radiotherapy (SBRT) and radiation biology at Stanford. His laboratory pioneered discoveries linking endoplasmic reticulum stress to radiation resistance and tumor hypoxia, while his clinical research established SBRT as a viable treatment for pancreatic cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Pancreatic Cancer SBRT
Developed and validated stereotactic body radiotherapy protocols for locally advanced pancreatic cancer at Stanford, demonstrating feasibility, safety, and promising local control rates.
Endoplasmic Reticulum Stress and Radiation Resistance
Discovered that tumor hypoxia activates endoplasmic reticulum stress pathways that confer radiation resistance, identifying novel therapeutic targets to overcome radioresistance in solid tumors.
Representative Works 代表性著作
Stereotactic body radiotherapy for locally advanced pancreatic cancer
International Journal of Radiation Oncology Biology Physics (2008)
Established clinical benchmarks for pancreatic SBRT, demonstrating high local control and manageable toxicity that spurred widespread adoption of the technique.
The unfolded protein response: a novel target for cancer therapy
Cancer Research (2009)
Linked endoplasmic reticulum stress signaling to radiation resistance in hypoxic tumors, opening new avenues for radiosensitization strategies.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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