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Translational Medicine / 转化医学Ovarian Cancer, Fanconi Anemia Pathway
Alan D'Andrea
MD
🏢Dana-Farber Cancer Institute🌐USA
Director, Susan F Smith Center for Women's Cancers
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Key Contributions
👥Biography 个人简介
Alan D'Andrea is a world leader in Fanconi anemia/BRCA pathway biology and PARP inhibitor resistance mechanisms. His laboratory has defined how 53BP1 loss, reversion mutations, and replication fork protection drive resistance. He directs the Smith Center at Dana-Farber.
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🧪Research Fields 研究领域
Fanconi anemia pathway
HR repair
PARP resistance mechanisms
DNA damage response
synthetic lethality
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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