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Translational Medicine / 转化医学Multiple Myeloma Bispecific Antibodies, Teclistamab

Ajai Chari

MD

🏢UCSF🌐USA

Professor

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Key Papers
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Key Contributions

👥Biography 个人简介

Ajai Chari has contributed to the development of bispecific antibody therapy for myeloma, including teclistamab (BCMA x CD3) and talquetamab (GPRC5D x CD3) — off-the-shelf T cell-engaging bispecific antibodies that achieve deep responses in relapsed/refractory myeloma without the complexity and delay of manufacturing patient-specific CAR-T cells. These agents are transforming the relapsed myeloma treatment landscape.

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🧪Research Fields 研究领域

teclistamab BCMA bispecific myeloma
talquetamab GPRC5D bispecific
elranatamab bispecific myeloma
MajesTEC trials myeloma
off-the-shelf bispecific myeloma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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