Omid Hamid
奥米德·哈米德
MD
Chief of Research and Immuno-Oncology, Director of Melanoma Therapeutics研究与免疫肿瘤学主任，黑色素瘤治疗主任
👥Biography 个人简介
Omid Hamid is a leading melanoma immunotherapy specialist at The Angeles Clinic, renowned for his pivotal role in pembrolizumab's clinical development. He has led more than 200 clinical trials and is recognized globally for early-phase immunotherapy research, novel combination strategies, and advancing care for advanced melanoma.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Pembrolizumab Clinical Development
Led KEYNOTE-001, the pivotal first-in-human pembrolizumab trial in advanced melanoma, providing foundational efficacy and safety data that supported FDA breakthrough designation and approval.
Combination Immunotherapy Strategies
Pioneered clinical trials combining checkpoint inhibitors with oncolytic viruses, vaccines, and targeted agents, exploring novel strategies to overcome immunotherapy resistance in melanoma.
Early Phase Trial Leadership
Directed over 200 first-in-human and early phase oncology trials, establishing The Angeles Clinic as a premier site for novel immuno-oncology drug development.
Representative Works 代表性著作
Safety and Tumor Responses with Lambrolizumab (Anti-PD-1) in Melanoma (KEYNOTE-001)
New England Journal of Medicine (2013)
Pivotal first-in-human pembrolizumab study demonstrating remarkable response rates and safety, establishing the foundation for FDA approval and global clinical development.
Five-Year Survival Outcomes for Patients with Advanced Melanoma Treated with Pembrolizumab (KEYNOTE-001)
Journal of Clinical Oncology (2019)
Long-term follow-up showing durable 5-year survival benefit with pembrolizumab, confirming the curative potential of anti-PD-1 therapy in melanoma.
Phase I Study of the Anti-PD-L1 Antibody MPDL3280A Combined with Bevacizumab in Patients with Metastatic Melanoma
Clinical Cancer Research (2017)
Demonstrated feasibility and promising activity of PD-L1 plus anti-angiogenic combination in melanoma, informing future combination strategies.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
University of California, Los Angeles (UCLA)
Caroline Robert
Institut Gustave Roussy
Jedd Wolchok
Memorial Sloan Kettering Cancer Center / Weill Cornell Medicine
Keith Flaherty
Massachusetts General Hospital / Harvard Medical School
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