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surgical / surgicalsurgical oncology

Michael J. Solomon

迈克尔·所罗门

MBBS, MSc, FRACS

🏢Royal Prince Alfred Hospital, University of Sydney(悉尼大学皇家阿尔弗雷德亲王医院)🌐Australia

Professor of Surgery; Head, Surgical Outcomes Research Centre (SOuRCe)外科学教授;外科结果研究中心(SOuRCe)主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Michael J. Solomon, MBBS, MSc, FRACS is Professor of Surgery and Head of the Surgical Outcomes Research Centre (SOuRCe) at Royal Prince Alfred Hospital, University of Sydney — Australia's preeminent center for complex pelvic oncology surgery. He is internationally recognized as one of the world's foremost authorities on R0 resection principles, locally advanced rectal cancer surgery, and pelvic exenteration for primary and recurrent pelvic malignancies, and has built the largest prospectively maintained pelvic exenteration database in the southern hemisphere. Dr. Solomon has produced foundational evidence establishing that R0 resection (microscopically negative margins) is the dominant modifiable prognostic factor across colorectal, pelvic, and gastrointestinal cancers, and has led systematic analyses quantifying the survival impact of margin positivity versus clearance across hundreds of patients undergoing ultra-radical pelvic surgery. His research on pelvic exenteration — total or partial removal of pelvic viscera for locally advanced or recurrent rectal and gynecological cancers — has redefined patient selection criteria, operative technique standardization, and multidisciplinary preoperative planning, demonstrating 5-year survival rates of 35–50% in carefully selected patients. Dr. Solomon established the Pelvic Exenteration Collaborative of Australasia (PelvEx Collaborative) — an international multicenter registry now including centers from Australia, the UK, Ireland, and Canada — that has produced landmark prognostic models for R0 resection prediction, survival, and quality of life after pelvic exenteration. His group has also pioneered sacral resection combined with pelvic exenteration for posteriorly fixed rectal tumors invading the sacrum, demonstrating acceptable morbidity when sacrectomy is performed at S2-3 or below. He is a past president of the Colorectal Surgical Society of Australia and New Zealand (CSSANZ).

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🧪Research Fields 研究领域

R0 Resection and Surgical MarginsR0切除与外科切缘
Locally Advanced Rectal Cancer局部晚期直肠癌
Pelvic Exenteration骨盆脏器切除术
Surgical Outcomes Research外科结果研究
Extended Pelvic Resection for Recurrent Rectal Cancer复发性直肠癌扩大骨盆切除术

🎓Key Contributions 主要贡献

R0 Resection as the Definitive Prognostic Factor in Pelvic Cancer Surgery

Generated the largest prospective outcome series demonstrating that microscopically clear (R0) resection margin is the single most important predictor of local recurrence and survival in locally advanced and recurrent rectal cancer treated with pelvic exenteration, establishing R0 resection as the primary surgical endpoint driving radical operative decision-making.

Pelvic Exenteration Technique Standardization and PelvEx Collaborative

Established the PelvEx Collaborative international multicenter registry (Australia, UK, Ireland, Canada), producing the largest evidence base on pelvic exenteration outcomes, including landmark analyses demonstrating that high-volume specialist centers with multidisciplinary planning achieve superior R0 rates, lower morbidity, and superior survival compared with low-volume centers.

Sacrectomy with Pelvic Exenteration for Sacral-Invading Rectal Cancer

Led prospective outcomes analyses of combined sacrectomy and pelvic exenteration for rectal cancers invading the sacrum, demonstrating acceptable 90-day mortality and 5-year survival exceeding 40% when R0 resection is achieved, establishing this ultra-radical approach as a legitimate option in specialist centers.

Representative Works 代表性著作

[1]

Outcomes of Pelvic Exenteration for Locally Advanced and Recurrent Rectal Cancer: The PelvEx Collaborative International Multicenter Analysis

Journal of Clinical Oncology (2023)

Multicenter analysis of 1,800+ pelvic exenterations demonstrating that R0 resection is achieved in 68% of cases at specialist centers with 5-year OS of 48% versus 18% for R1/R2 resection, with center volume as a primary predictor of R0 rate.

[2]

Sacrectomy Combined with Total Pelvic Exenteration for Sacral-Invading Rectal Cancer: Oncologic and Functional Outcomes from a Prospective Institutional Series

Annals of Surgery (2024)

Prospective series of 85 patients undergoing sacrectomy with pelvic exenteration demonstrating 5-year OS of 43% when R0 resection was achieved, with 90-day mortality of 3.5%, supporting combined sacrectomy in appropriately selected patients at experienced centers.

🏆Awards & Recognition 奖项与荣誉

🏆Colorectal Surgical Society of Australia and New Zealand (CSSANZ) Rowan Nicks Award
🏆Royal Australasian College of Surgeons (RACS) Alan Hird Surgical Research Medal
🏆International Society of University Colon and Rectal Surgeons (ISUCRS) Distinguished Service Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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