Alessandro Gronchi
亚历山德罗·格隆基
MD
Director, Department of Surgery; Head, Sarcoma Surgery Program外科部主任;肉瘤外科项目负责人
👥Biography 个人简介
Alessandro Gronchi is the director of surgery at the Istituto Nazionale dei Tumori in Milan and the world's foremost authority on retroperitoneal sarcoma surgery. He founded and co-chairs the TransAtlantic Retroperitoneal Sarcoma Working Group (TARPSWG), which has produced landmark consensus guidelines and prospective data redefining surgical strategy for this challenging disease. His research has clarified the role of extended vs. standard resection for retroperitoneal liposarcoma and established the critical importance of histotype-tailored surgical approaches.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
TARPSWG — Retroperitoneal Sarcoma Surgery Standards
Co-founded and led TARPSWG, a multinational collaboration producing the definitive consensus statement on surgical management of primary retroperitoneal sarcoma, establishing compartmental resection principles and histotype-specific surgical guidelines adopted internationally.
Extended vs. Standard Resection for Retroperitoneal Liposarcoma
Led the STRASS randomized phase III trial comparing extended resection with standard resection for primary retroperitoneal sarcoma, providing the only prospective randomized data in this disease and clarifying the marginal benefit of extended compartmental surgery specifically in dedifferentiated liposarcoma.
Histotype-Tailored Surgery and Nomogram Development
Developed and externally validated the Memorial Sloan Kettering/INT-Milan sarcoma nomograms predicting recurrence and survival after resection of retroperitoneal sarcoma, enabling individualized counseling and decision-making for patients and clinicians.
Representative Works 代表性著作
Preoperative Radiotherapy plus Surgery versus Surgery Alone for Patients with Primary Retroperitoneal Sarcoma (STRASS): A Phase 3, Open-Label, Randomised Controlled Trial
The Lancet Oncology (2020)
STRASS phase III trial evaluating neoadjuvant radiotherapy in retroperitoneal sarcoma, showing histotype-specific effects.
Multidisciplinary Management of Primary Retroperitoneal Sarcoma: Consensus Guidelines from TARPSWG
Annals of Surgical Oncology (2018)
International consensus guidelines for retroperitoneal sarcoma surgical management from the TARPSWG collaboration.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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