Kiran Musunuru
M.D., Ph.D., M.P.H.
Professor of Cardiovascular Medicine
👥Biography 个人简介
Kiran Musunuru is a leader in applying in vivo gene editing to cardiovascular disease. His work has demonstrated that CRISPR-based editing of PCSK9 in liver can durably lower cholesterol, with implications for cancer prevention in high-risk patients. Musunuru advances single-dose gene editing cures for chronic diseases.
Kiran Musunuru是将体内基因编辑应用于心血管疾病的领导者。他的工作表明，基于CRISPR的肝脏PCSK9编辑可以持久降低胆固醇，对高风险患者的癌症预防具有意义。Musunuru推进慢性疾病的单剂量基因编辑治愈方法。
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
PCSK9 Editing
Demonstrated in vivo base editing to permanently lower cholesterol.
Cardiometabolic Gene Therapy
Advancing gene editing for cardiovascular risk reduction.
Representative Works 代表性著作
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Nature (2021)
Base editing for cholesterol lowering.
📄Data Sources 数据来源
Last updated: 2026-03-05 | All information from publicly available academic sources
Related Experts 相关专家
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University of Pennsylvania
Guangping Gao
University of Massachusetts Chan Medical School
Federico Mingozzi
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Feng Zhang
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