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Gene Therapy / 基因治疗Gene Silencing

Drew Weissman

M.D., Ph.D.

🏢University of Pennsylvania🌐USA

Roberts Family Professor of Vaccine Research

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Drew Weissman collaborated with Katalin Karikó to develop modified mRNA technology that enabled COVID-19 vaccines and is now being applied to cancer. His laboratory continues to advance mRNA therapeutics for infectious diseases, cancer, and genetic disorders, with multiple programs in clinical development.

Drew Weissman与Katalin Karikó合作开发了修饰mRNA技术,使COVID-19疫苗成为可能,现在正被应用于癌症。他的实验室继续推进用于传染病、癌症和遗传疾病的mRNA治疗,多个项目正在临床开发中。

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🧪Research Fields 研究领域

mRNA VaccinesmRNA疫苗
RNA BiologyRNA生物学
Immunology免疫学

🎓Key Contributions 主要贡献

mRNA Technology

Co-developed modified mRNA technology with Karikó.

Lipid Nanoparticles

Advanced LNP formulations for mRNA delivery.

Representative Works 代表性著作

[1]

Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity

Molecular Therapy (2008)

Demonstration of improved mRNA translation with modifications.

🏆Awards & Recognition 奖项与荣誉

🏆Nobel Prize in Physiology or Medicine (2023)
🏆Lasker-DeBakey Clinical Medical Research Award (2021)

📄Data Sources 数据来源

Last updated: 2026-03-05 | All information from publicly available academic sources

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