Chrysalyne Schmults
克莉萨林·施穆尔茨
MD, MSCE
Director, High-Risk Skin Cancer Program; Associate Professor of Dermatology高危皮肤癌项目主任；皮肤科副教授
👥Biography 个人简介
Chrysalyne Schmults is the leading expert in high-risk cutaneous squamous cell carcinoma (cSCC) at Brigham and Women's Hospital, directing the nation's premier high-risk skin cancer program. She created the BWH tumor classification system for cSCC, advanced Mohs surgery outcomes research, and has shaped evidence-based guidelines for cSCC management.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
cSCC Risk Stratification
Developed and validated the Brigham and Women's Hospital (BWH) tumor classification system for cutaneous squamous cell carcinoma, enabling superior identification of high-risk tumors compared to prior staging systems.
Mohs Surgery Outcomes Research
Led large-scale outcomes research on Mohs micrographic surgery for cSCC and basal cell carcinoma, defining cure rates, recurrence predictors, and optimal patient selection criteria.
Multidisciplinary High-Risk Skin Cancer Care
Established and directs the BWH High-Risk Skin Cancer Program, a multidisciplinary clinic model integrating dermatology, radiation oncology, and medical oncology for complex cSCC cases.
Representative Works 代表性著作
Development and Validation of a New American Joint Committee on Cancer Staging System for Cutaneous Squamous Cell Carcinoma
Journal of Clinical Oncology (2011)
Proposed the BWH staging system demonstrating superior discrimination of high-risk cSCC compared to AJCC staging, now incorporated in clinical practice guidelines.
Tumor Upstaging Using the Brigham and Women's Hospital System for Cutaneous Squamous Cell Carcinoma Staging
JAMA Dermatology (2014)
Validated BWH staging system superiority in predicting nodal metastasis and disease-specific death across multi-institutional cohorts.
Outcomes of Mohs Surgery for Cutaneous Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
JAMA Dermatology (2013)
Established evidence-based benchmarks for Mohs surgery recurrence rates in cSCC, supporting guideline development for appropriate use criteria.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Keith Flaherty
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