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clinical / clinicalesophageal cancer Japan

Takahiro Tsushima

津岛贵宏

MD, PhD

🏢Shizuoka Cancer Center(静冈癌症中心)🌐Japan

Division Head, Gastrointestinal Oncology消化系统肿瘤科主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Takahiro Tsushima is a Japanese GI oncologist specializing in esophageal squamous cell carcinoma, which has high incidence in Japan and distinctive biology from Western esophageal adenocarcinoma. He has contributed to JCOG esophageal cancer trials and has participated in global immunotherapy trials of pembrolizumab and nivolumab in esophageal SCC with Asian patient enrichment. Tsushima has contributed to Japanese evidence on dcetaxel-based second-line regimens, neoadjuvant chemotherapy standards, and immunotherapy biomarker evaluation in Japanese esophageal SCC. His research addresses the specific challenges of esophageal SCC in Japanese and Asian populations.

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🧪Research Fields 研究领域

esophageal squamous cell carcinoma食管鳞状细胞癌
KEYNOTE-590 AsiaKEYNOTE-590亚洲
CheckMate 648 esophagealCheckMate 648食管
Japan esophageal cancer trials日本食管癌试验
docetaxel esophageal多西他赛食管癌

🎓Key Contributions 主要贡献

Japanese Esophageal SCC Clinical Evidence

Contributed to JCOG trials defining chemotherapy standards for esophageal SCC in Japan and provided Japanese patient data to global immunotherapy trials, enabling regulatory decisions incorporating Asian patient populations.

Immunotherapy in Asian Esophageal SCC

Contributed to Asian subgroup analyses of KEYNOTE-590 and CheckMate 648 demonstrating immunotherapy benefit in Japanese esophageal SCC, supporting adoption of these regimens in Japanese clinical practice.

Representative Works 代表性著作

[1]

Japanese Experience with Nivolumab in Esophageal Squamous Cell Carcinoma (ATTRACTION-3)

Lancet Oncology (2019)

Asian pivotal trial of nivolumab in esophageal SCC.

[2]

Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma in Japan

Japanese Journal of Clinical Oncology (2020)

Japanese evidence on neoadjuvant chemotherapy standards in esophageal SCC.

🏆Awards & Recognition 奖项与荣誉

🏆Japanese Society of Medical Oncology Young Researcher Award
🏆Shizuoka Cancer Center Excellence Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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