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clinical / clinicalRare Genetic Cancers & NF1

Victor-Felix Mautner

维克托·毛特纳

MD

🏢University Medical Center Hamburg-Eppendorf(汉堡-埃彭多夫大学医学中心)🌐Germany

Professor of Neurology; Head, NF Outpatient Clinic神经病学教授;NF门诊主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Prof. Mautner is Europe's foremost authority on NF1, directing one of the world's largest NF outpatient clinics at Hamburg-Eppendorf. He pioneered whole-body MRI surveillance protocols for NF1 tumor detection and malignant transformation monitoring, and leads major European NF1 epidemiology and natural history studies.

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🧪Research Fields 研究领域

Neurofibromatosis Type 11型神经纤维瘤病
Whole-Body MRI in NF1NF1全身MRI
NF1 Tumor Burden AssessmentNF1肿瘤负荷评估
NF1 European Cohort StudiesNF1欧洲队列研究
NF1 MPNST SurveillanceNF1恶性周围神经鞘膜瘤监测
NF1 Long-Term Natural HistoryNF1长期自然史

🎓Key Contributions 主要贡献

Whole-Body MRI for NF1 Surveillance

Pioneered whole-body MRI as a comprehensive surveillance tool for NF1, enabling systematic detection of internal plexiform neurofibromas and early identification of MPNST transformation before clinical symptoms develop.

NF1 Epidemiology and Natural History

Conducted landmark European NF1 epidemiology studies establishing complication rates, malignancy risks, and natural history data from the world's largest NF1 patient registry, providing evidence base for clinical guidelines.

Representative Works 代表性著作

[1]

Whole-Body MRI in Neurofibromatosis Type 1 for Detection of Internal Plexiform Neurofibromas

Neurology (2008)

Established whole-body MRI as a systematic screening tool for NF1 internal tumors, demonstrating its superiority over clinical examination alone for detecting plexiform neurofibromas and MPNST.

[2]

Distribution and Risk of Malignancy in 69 Consecutively Resected Neurofibromas

Archives of Dermatology (1997)

Seminal study characterizing neurofibroma malignancy risk in NF1, establishing clinicopathological correlations that informed surveillance recommendations and surgical decision-making.

🏆Awards & Recognition 奖项与荣誉

🏆Deutsche Gesellschaft für Neurologie Research Award
🏆European NF Consortium Lifetime Achievement Award
🏆Children's Tumor Foundation International Research Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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