Ute Bartels
乌特·巴特尔斯
MD
Staff Physician, Haematology/Oncology; Associate Professor of Paediatrics血液肿瘤科主治医师；儿科副教授
👥Biography 个人简介
Ute Bartels is a dedicated pediatric neuro-oncologist at SickKids Toronto with extensive expertise in DIPG clinical trials, convection-enhanced delivery strategies, and compassionate end-of-life care for children with brain stem tumors, and has led numerous first-in-child studies for this devastating disease.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
DIPG Clinical Trial Leadership
Led and co-led over 15 phase I/II clinical trials in pediatric DIPG at SickKids, including ONC201, panobinostat combinations, and immunotherapy approaches, enrolling patients globally.
Convection-Enhanced Delivery
Pioneered clinical application of CED for direct intratumoral drug delivery in DIPG at SickKids, establishing surgical and imaging protocols for safe repeated infusions in children.
DIPG Natural History and Palliative Care
Conducted detailed natural history studies of DIPG providing the most comprehensive data on disease progression, steroid use, and quality-of-life endpoints informing trial design and family counseling.
Representative Works 代表性著作
Convection-enhanced delivery of panobinostat in pediatric DIPG
Journal of Neurosurgery: Pediatrics (2020)
First report of CED-delivered panobinostat in DIPG patients demonstrating feasibility and drug distribution within the pons.
DIPG natural history and end-of-life: a population-based study
Neuro-Oncology (2019)
Comprehensive natural history analysis of 170 DIPG patients informing prognostic counseling and clinical trial endpoint selection.
Clinical trials in DIPG: a systematic review
Pediatric Blood & Cancer (2022)
Systematic review of all DIPG trials 2000–2021 identifying lessons learned and priority strategies for future drug development.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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University of California, San Francisco (UCSF)
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Yale School of Medicine / Yale Cancer Center
Sara M. Tolaney
Dana-Farber Cancer Institute / Harvard Medical School
Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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留下邮箱，当我们发布与 Ute Bartels（The Hospital for Sick Children (SickKids), University of Toronto）相关的新研究或访谈时，我们会通知你。
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