Learn more →
Back to Expert Scholars
Immunotherapy / 免疫治疗Checkpoint Inhibitors

Thomas F. Gajewski

M.D., Ph.D.

🏢University of Chicago🌐USA

Professor of Pathology and Medicine

1
Key Papers
2
Key Contributions

👥Biography 个人简介

Thomas Gajewski is a leader in understanding the tumor microenvironment and innate immune mechanisms that regulate anti-tumor immunity. His research has revealed the STING pathway's role in spontaneous anti-tumor T cell responses and developed strategies to convert non-T cell-inflamed tumors to inflamed phenotypes. Gajewski's work informs rational combination immunotherapy approaches.

Thomas Gajewski是理解肿瘤微环境和调节抗肿瘤免疫的先天免疫机制的领导者。他的研究揭示了STING通路在自发性抗肿瘤T细胞反应中的作用,并开发了将非T细胞浸润肿瘤转化为浸润表型的策略。Gajewski的工作为合理的联合免疫治疗方法提供了信息。

Share:

🧪Research Fields 研究领域

Tumor Microenvironment肿瘤微环境
Innate Immunity先天免疫
Cancer Immunotherapy癌症免疫治疗

🎓Key Contributions 主要贡献

STING Pathway

Identified STING as critical for spontaneous anti-tumor T cell priming.

T Cell-Inflamed Phenotype

Characterized molecular determinants of T cell-inflamed versus non-inflamed tumors.

Representative Works 代表性著作

[1]

STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon responses

Immunity (2014)

STING pathway in anti-tumor immunity.

📄Data Sources 数据来源

Last updated: 2026-03-04 | All information from publicly available academic sources

关注 Thomas F. Gajewski 的研究动态

Follow Thomas F. Gajewski's research updates

留下邮箱,当我们发布与 Thomas F. Gajewski(University of Chicago)相关的新研究或访谈时,我们会通知你。

我们不会泄露你的信息,也不会发送无关内容。随时可以退订。

Explore More Experts

Discover the researchers shaping the future of cancer treatment