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breast-oncology / breast-oncologyTriple-Negative Breast Cancer

Sylvia Adams

西尔维亚·亚当斯

MD

🏢NYU Langone Health / Perlmutter Cancer Center(纽约大学朗格尼健康中心/珀尔马特癌症中心)🌐USA

Director of Breast Cancer Medicine Program乳腺癌药物治疗项目主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Sylvia Adams is a pioneer in TNBC immunotherapy at NYU Langone, whose early work on tumor-infiltrating lymphocytes shaped understanding of immune contexture in breast cancer. She has led multiple immunotherapy trials and is a leading voice in precision breast oncology.

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🧪Research Fields 研究领域

Breast Oncology乳腺肿瘤学
TNBC三阴性乳腺癌
Immunotherapy免疫治疗
Tumor Microenvironment肿瘤微环境

🎓Key Contributions 主要贡献

Tumor-Infiltrating Lymphocytes in TNBC

Established TILs as a prognostic and predictive biomarker in TNBC, influencing patient selection for immunotherapy and clinical trial design.

Immunotherapy Combinations in Breast Cancer

Led clinical trials of checkpoint inhibitors in TNBC, contributing evidence that informs the integration of immunotherapy into early and metastatic treatment.

Representative Works 代表性著作

[1]

Atezolizumab plus nab-paclitaxel in metastatic TNBC (IMpassion130)

New England Journal of Medicine (2018)

Key trial showing atezolizumab benefit in PD-L1+ TNBC, supporting first-line immunotherapy use and biomarker-driven selection.

[2]

Prognostic significance of TILs in TNBC

Journal of Clinical Oncology (2014)

Demonstrated TILs predict improved survival in TNBC, establishing immune infiltration as a critical prognostic variable.

🏆Awards & Recognition 奖项与荣誉

🏆Conquer Cancer Foundation Career Development Award
🏆NYU Clinical and Translational Science Award
🏆Susan G. Komen Career Catalyst Research Grant

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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