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breast-oncology / breast-oncologyBRCA-Related Breast Cancer

Erica Mayer

埃丽卡·迈尔

MD, MPH

🏢Dana-Farber Cancer Institute(丹娜-法伯癌症研究所)🌐USA

Senior Physician, Breast Oncology Program乳腺肿瘤项目高级医师

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Erica Mayer is a leading authority on BRCA-related and hereditary breast cancer at Dana-Farber. Her research has shaped the clinical use of PARP inhibitors in BRCA-mutated breast cancer and established survivorship and genetic testing frameworks for high-risk patients.

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🧪Research Fields 研究领域

Breast Oncology乳腺肿瘤学
Germline BRCA胚系BRCA突变
PARP InhibitorsPARP抑制剂
Hereditary Breast Cancer遗传性乳腺癌

🎓Key Contributions 主要贡献

PARP Inhibitors in BRCA-Mutated Breast Cancer

Contributed to pivotal olaparib and talazoparib trials demonstrating PFS benefit in germline BRCA-mutated metastatic breast cancer, supporting FDA approvals.

Hereditary Cancer Risk and Survivorship

Developed patient education and risk management models for BRCA carriers, improving genetic counseling and surveillance strategies in high-risk breast cancer populations.

Representative Works 代表性著作

[1]

Olaparib for metastatic breast cancer in patients with a germline BRCA mutation (OlympiAD)

New England Journal of Medicine (2017)

Landmark trial demonstrating olaparib superiority over chemotherapy in germline BRCA-mutated HER2-negative metastatic breast cancer.

[2]

PARP inhibition in early-stage BRCA-mutated breast cancer (OlympiA)

New England Journal of Medicine (2021)

Adjuvant olaparib significantly improved invasive DFS in high-risk germline BRCA-mutated early breast cancer.

🏆Awards & Recognition 奖项与荣誉

🏆Dana-Farber Department of Medicine Research Excellence Award
🏆Conquer Cancer Foundation Career Development Award
🏆Susan G. Komen Promise Grant Investigator

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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