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cardio-oncology / cardio-oncologyHER2 Therapy Cardiotoxicity

Susan Dent

苏珊·登特

MD, FRCPC

🏢Duke University Medical Center(杜克大学医学中心)🌐USA

Professor of Medicine, Director of Cardio-Oncology Program医学教授,肿瘤心脏病学项目主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Professor and Director of Cardio-Oncology at Duke University, Dr. Dent is a world authority on cardiac toxicity of HER2-targeted therapies in breast cancer. She led the SAFE-HEaRt trial and has shaped international guidelines for cardiac monitoring.

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🧪Research Fields 研究领域

Cardio-oncology肿瘤心脏病学
HER2-Targeted Therapy CardiotoxicityHER2靶向治疗心脏毒性
Breast Cancer Cardiology乳腺癌心脏病学

🎓Key Contributions 主要贡献

SAFE-HEaRt Trial

Led SAFE-HEaRt trial, enabling HER2-therapy continuation with cardiac dysfunction under optimized cardioprotection management.

International HER2 Cardio-Oncology Guidelines

Developed international cardio-oncology guidelines for HER2-targeted therapy cardiac monitoring, adopted globally.

Duke Cardio-Oncology Program

Built Duke Cardio-Oncology Program integrating oncology and cardiology for comprehensive survivorship care.

Representative Works 代表性著作

[1]

SAFE-HEaRt: Treating Patients with HER2-Positive Breast Cancer and Reduced LVEF

JACC: CardioOncology (2019)

Demonstrated safety of continuing HER2 therapy with optimized cardiac management in compromised patients.

[2]

Cardiotoxicity of HER2-Targeted Therapies: Current Status and Future Directions

Journal of Clinical Oncology (2016)

Comprehensive review guiding cardiac monitoring in HER2-positive breast cancer treatment.

🏆Awards & Recognition 奖项与荣誉

🏆International CardiOncology Society Distinguished Investigator Award
🏆Canadian Cardiovascular Society Award of Excellence
🏆Duke Cancer Institute Research Innovation Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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