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cardio-oncology / cardio-oncologyImmune Checkpoint Inhibitor Cardiotoxicity

Javid Moslehi

贾维德·莫斯莱希

MD

🏢University of California San Francisco (UCSF)(加州大学旧金山分校)🌐USA

Professor of Medicine, Director of Cardio-Oncology Program医学教授,肿瘤心脏病学项目主任

61
h-index
2
Key Papers
3
Awards
3
Key Contributions

👥Biography 个人简介

World leader in immune checkpoint inhibitor (ICI) cardiotoxicity at UCSF. Dr. Moslehi pioneered research on ICI-associated myocarditis, established global registries, and translated basic science into clinical protocols shaping international guidelines for managing immunotherapy cardiac complications.

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🧪Research Fields 研究领域

Cardio-oncology肿瘤心脏病学
Immune Checkpoint Inhibitor Cardiotoxicity免疫检查点抑制剂心脏毒性
Myocarditis心肌炎

🎓Key Contributions 主要贡献

Global ICI Myocarditis Registry

Pioneered global registry (WHO VigiBase) for immune checkpoint inhibitor-associated myocarditis, enabling epidemiological characterization.

Clinical Characterization of ICI-Myocarditis

Characterized fatal ICI-myocarditis, establishing clinical recognition criteria and standardized management protocols adopted internationally.

PD-1 Cardiac Biology

Discovered the role of the PD-1/PD-L1 axis in cardiac homeostasis and immune tolerance, advancing mechanistic understanding.

Representative Works 代表性著作

[1]

Cardiovascular Actions and Toxicities of Therapies for Cancer

New England Journal of Medicine (2016)

Seminal review defining the field of cardio-oncology for modern cancer therapies.

[2]

Myocarditis with Use of Checkpoint Inhibitors for Cancer

New England Journal of Medicine (2018)

Landmark description of ICI-associated myocarditis pattern, frequency, and outcomes.

🏆Awards & Recognition 奖项与荣誉

🏆American Heart Association Distinguished Scientist Award
🏆ASCO Conquer Cancer Career Development Award
🏆NIH Director's New Innovator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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