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clinical / clinicalThyroid & Endocrine Cancers

Sophie Leboulleux

苏菲·勒布鲁

MD, PhD

🏢Gustave Roussy Cancer Campus(古斯塔夫·鲁西癌症中心)🌐France

Head, Thyroid Cancer Unit; Professor of Endocrinology甲状腺癌科主任;内分泌学教授

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h-index
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Key Papers
3
Awards
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Key Contributions

👥Biography 个人简介

Dr. Sophie Leboulleux leads the thyroid cancer program at Gustave Roussy, Europe's largest cancer center. A key contributor to European and international thyroid cancer trials, she has advanced knowledge of radioiodine-refractory differentiated thyroid cancer management and molecular imaging strategies for risk stratification.

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🧪Research Fields 研究领域

Radioiodine-Refractory Thyroid Cancer放射性碘难治性甲状腺癌
Lenvatinib乐伐替尼
European Clinical Trials欧洲临床试验
Differentiated Thyroid Cancer分化型甲状腺癌
Molecular Imaging分子影像

🎓Key Contributions 主要贡献

European Radioiodine-Refractory Thyroid Cancer Trials

Led and participated in pivotal European multicenter trials evaluating lenvatinib, sorafenib, and novel targeted agents in radioiodine-refractory DTC, contributing large patient cohorts and translational biomarker substudies.

Molecular Imaging and Risk Stratification

Advanced the use of FDG-PET/CT and other molecular imaging modalities for predicting outcomes and guiding treatment decisions in differentiated and poorly differentiated thyroid cancers.

Representative Works 代表性著作

[1]

Lenvatinib versus placebo in radioiodine-refractory thyroid cancer (SELECT trial): European perspective

European Journal of Cancer (2016)

European cohort analysis of the SELECT trial confirming lenvatinib benefit, with subgroup analyses informing patient selection and management in European practice.

[2]

FDG-PET/CT for the diagnosis and follow-up of thyroid cancer with serum thyroglobulin elevation

Journal of Nuclear Medicine (2017)

Prospective study validating FDG-PET/CT utility in thyroid cancer surveillance, establishing clinical guidelines for molecular imaging use.

🏆Awards & Recognition 奖项与荣誉

🏆European Thyroid Association Research Award
🏆Gustave Roussy Research Excellence Prize
🏆Société Française d'Endocrinologie Distinguished Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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