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targeted-therapy / targeted-therapyMelanoma Targeted Therapy

Simone Mocellin

西蒙·莫切林

MD, PhD

🏢University of Padova(帕多瓦大学)🌐Italy

Professor of Surgical Oncology and Director, Melanoma Unit外科肿瘤学教授兼黑色素瘤科主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Simone Mocellin is a European leader in melanoma targeted therapy and surgical oncology. He has contributed extensively to clinical and translational research on BRAF/MEK inhibitors and has led meta-analyses shaping evidence-based melanoma treatment guidelines internationally.

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🧪Research Fields 研究领域

Melanoma Targeted Therapy黑色素瘤靶向治疗
BRAF/MEK InhibitorsBRAF/MEK抑制剂
Surgical Oncology外科肿瘤学
Cancer Immunotherapy肿瘤免疫治疗

🎓Key Contributions 主要贡献

BRAF/MEK Inhibitor Clinical Outcomes in Melanoma

Conducted systematic reviews and meta-analyses of BRAF and MEK inhibitor trials in advanced melanoma, providing evidence synthesis informing treatment guidelines and combination strategies.

Telomerase as a Cancer Target

Investigated telomerase biology in cancer and performed comprehensive meta-analyses of telomerase-targeted therapies, contributing to understanding of telomere maintenance as a therapeutic vulnerability.

Representative Works 代表性著作

[1]

Telomerase and the search for the end of cancer

Trends in Molecular Medicine (2013)

Reviewed telomerase as a universal cancer target, synthesizing preclinical and clinical evidence for telomere-targeting strategies in oncology.

[2]

Targeted therapy for melanoma: a meta-analysis of randomized controlled trials

Annals of Oncology (2015)

Large-scale meta-analysis quantifying survival benefits of BRAF/MEK inhibitor combinations versus monotherapy in BRAF-mutant advanced melanoma patients.

🏆Awards & Recognition 奖项与荣誉

🏆Italian Society of Surgical Oncology (SICO) Award
🏆European Association for Cancer Research Young Investigator Award
🏆Melanoma Research Foundation Clinical Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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