Shelley Hwang
谢利·黄
MD, MPH
Mary and Deryl Hart Distinguished Professor of Surgery; Chief, Breast SurgeryMary and Deryl Hart外科杰出教授；乳腺外科主任
👥Biography 个人简介
Shelley Hwang is a pioneering breast surgical oncologist and quality advocate who leads the landmark COMET trial testing active surveillance versus standard surgery for low-risk DCIS. She champions value-based care and de-escalation of treatment for low-risk breast cancer, seeking to reduce overtreatment while preserving patient quality of life.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
COMET Active Surveillance Trial
Led the COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial, the first randomized US trial evaluating active surveillance versus surgery for low-risk DCIS, with quality of life as a co-primary endpoint.
De-escalation of Breast Cancer Treatment
Advanced evidence and advocacy for treating low-risk breast cancer with less-aggressive approaches, improving quality of life while maintaining safety—a paradigm shift in breast cancer care delivery.
Patient-Centered Outcomes in Breast Surgery
Embedded shared decision-making tools and PRO collection into breast surgery practice at Duke, and led research on how treatment choices align with patient values for low-risk breast cancer.
Representative Works 代表性著作
Active Surveillance for DCIS: The COMET Trial
NEJM Evidence (2024)
Results of the landmark COMET randomized trial showing non-inferiority of active surveillance versus surgery for quality of life in low-risk DCIS patients.
Risk-Stratified Management of DCIS: What Does the Future Hold?
Journal of Clinical Oncology (2019)
Framework for risk-stratified approaches to DCIS management, integrating molecular markers and patient preferences to individualize treatment.
Patient Values, Preferences, and Low-Risk DCIS Decision Making
Annals of Surgical Oncology (2021)
Survey study revealing how patient values and risk tolerance drive treatment choices in low-risk DCIS, supporting tailored shared decision-making.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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