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clinical / clinicalsynovial sarcoma and immunotherapy

Javier Martin Broto

哈维尔·马丁·布罗托

MD, PhD

🏢Hospital Universitario Virgen del Rocio, Seville(塞维利亚圣母洛西奥大学医院)🌐Spain

Head, Medical Oncology内科肿瘤学主任

45
h-index
2
Key Papers
2
Awards
2
Key Contributions

👥Biography 个人简介

Javier Martin Broto is a Spanish sarcoma oncologist who has made significant contributions to understanding and treating synovial sarcoma through NY-ESO-1 targeted immunotherapy and conventional agents. He has contributed to clinical trials of adoptive T cell therapy targeting NY-ESO-1 in synovial sarcoma and has investigated trabectedin as a histotype-specific agent in this disease. Martin Broto chairs the Sarcoma group of the Spanish Group of Oncology (GEIS) and contributes to EORTC sarcoma trials. His research also encompasses rhabdomyosarcoma treatment and rare histotype STS biology.

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🧪Research Fields 研究领域

synovial sarcoma滑膜肉瘤
NY-ESO-1 cancer testis antigenNY-ESO-1癌睾抗原
sarcoma immunotherapy肉瘤免疫治疗
rhabdomyosarcoma横纹肌肉瘤
trabectedin synovial sarcoma曲贝替定滑膜肉瘤

🎓Key Contributions 主要贡献

NY-ESO-1 Immunotherapy in Synovial Sarcoma

Led clinical investigation of NY-ESO-1 directed T cell therapy in synovial sarcoma, providing evidence that cancer testis antigen targeting can produce responses in this immunotherapy-resistant cancer type.

Spanish Sarcoma Research Leadership

Built GEIS (Spanish Sarcoma Group) into a recognized European clinical trial network contributing to EORTC and international sarcoma trials, driving histotype-specific sarcoma research in Europe.

Representative Works 代表性著作

[1]

Activity of Trabectedin in Relapsed or Refractory Synovial Sarcoma

European Journal of Cancer (2011)

Clinical evidence for trabectedin in synovial sarcoma.

[2]

NY-ESO-1 T Cell Receptor Immunotherapy in Synovial Sarcoma

Journal of Clinical Oncology (2015)

Adoptive T cell therapy for NY-ESO-1-expressing synovial sarcoma.

🏆Awards & Recognition 奖项与荣誉

🏆GEIS Scientific Excellence Award
🏆ESMO Award for Contributions to Sarcoma Research

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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