Robert Negrin
罗伯特·内格林
MD
Professor of Medicine, Chief of Blood and Marrow Transplantation医学教授，血液与骨髓移植科主任
👥Biography 个人简介
Robert Negrin is a pioneer in hematopoietic stem cell transplantation at Stanford, renowned for elucidating regulatory T cell mechanisms in GvHD prevention and developing tolerance-based strategies for haploidentical transplantation.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Regulatory T Cells in GvHD
Demonstrated that adoptive transfer of regulatory T cells can suppress graft-versus-host disease while preserving graft-versus-tumor effects, transforming the field's approach to immune tolerance post-transplant.
Haploidentical HSCT
Advanced haploidentical transplantation protocols at Stanford, improving engraftment and reducing GvHD through refined T cell manipulation and post-transplant immunosuppression strategies.
Representative Works 代表性著作
Regulatory T cells prevent graft-versus-host disease following allogeneic hematopoietic cell transplantation
Blood (2021)
Landmark study demonstrating Treg-mediated GvHD suppression with preserved graft-versus-leukemia activity in clinical and preclinical models.
Haploidentical transplantation outcomes with post-transplant cyclophosphamide at Stanford
Biology of Blood and Marrow Transplantation (2022)
Comprehensive analysis of PT-Cy-based haploidentical HSCT outcomes demonstrating improved OS and reduced severe GvHD.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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