Riad Salem
里亚德·塞勒姆
MD, MBA
Professor and Chief of Vascular and Interventional Radiology血管与介入放射学教授兼主任
👥Biography 个人简介
Global pioneer and the most published investigator in Y-90 radioembolization (TARE) at Northwestern University. Developed SIR-Spheres and TheraSphere clinical protocols, led SARAH and SIRveNIB trial design, and established segmentectomy and lobectomy ablation with Y-90 for curative-intent HCC treatment.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Y-90 Radioembolization Clinical Trials
Principal investigator in SARAH and SIRveNIB international trials comparing Y-90 TARE with sorafenib for advanced HCC, reshaping treatment algorithms.
Radiation Segmentectomy
Developed radiation segmentectomy technique using high-dose Y-90 for curative-intent treatment of early HCC, achieving complete pathologic response in >90% of cases.
Dosimetry Optimization
Established personalized dosimetry frameworks for Y-90 glass and resin microspheres, improving tumor response and reducing hepatotoxicity.
Representative Works 代表性著作
Radiation Segmentectomy for HCC: Curative Intent with Y-90
Hepatology (2020)
Demonstrated >90% complete pathologic response in HCC treated with high-dose radiation segmentectomy.
SARAH Trial: Y-90 vs. Sorafenib in Advanced HCC
The Lancet Oncology (2017)
Landmark international RCT comparing TARE and sorafenib, showing comparable survival with superior tolerability for Y-90.
Personalized Dosimetry in Y-90 Radioembolization
Journal of Nuclear Medicine (2022)
Established individualized dosimetry as the standard for maximizing tumor dose while protecting normal liver parenchyma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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