Peter Park
朴彼得
PhD
Professor of Biomedical Informatics生物医学信息学教授
👥Biography 个人简介
Computational biologist and epigenomics pioneer whose work integrates single-cell genomics, chromatin structure, and somatic mutations to understand gene regulation in cancer. Developed key tools for ChIP-seq and single-cell analysis.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
ChIP-Seq Analysis
Developed SPP and other tools for ChIP-seq data analysis, enabling systematic study of histone modifications and transcription factor binding in cancer epigenomes.
Single-Cell Genomics
Advanced single-cell computational methods to dissect tumor heterogeneity, revealing rare cancer cell states and microenvironment interactions.
Somatic Structural Variants
Developed approaches to identify somatic structural variants in cancer genomes, uncovering complex rearrangements that drive oncogene activation.
Representative Works 代表性著作
Design and analysis of ChIP-seq experiments for DNA-binding proteins
Nature Biotechnology (2008)
Established statistical framework for ChIP-seq analysis, foundational to cancer epigenomics research.
Integrative analysis of 111 reference human epigenomes
Nature (2015)
Roadmap Epigenomics landmark study characterizing epigenomic variation across human tissues relevant to cancer.
Somatic HIST1H3B/C mutations cause hypoxia-independent activation of HIFs in clear cell renal cell carcinoma
Nature Genetics (2018)
Identified histone mutations activating oncogenic pathways in renal cell carcinoma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Mary-Claire King
University of Washington
Kenneth Offit
Memorial Sloan Kettering Cancer Center
Judy Garber
Dana-Farber Cancer Institute
Barbara Biesecker
RTI International / NHGRI
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