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Immunotherapy / 免疫治疗Bispecific AntibodiesBispecific T-cell Engager Pioneer

Peter Kufer

彼得·库弗

Ph.D.

🏢Amgen Research Munich(安进慕尼黑研究中心)🌐Germany

Vice President, BiTE TechnologyBiTE技术副总裁

2
Key Papers
2
Awards
2
Key Contributions

👥Biography 个人简介

Peter Kufer is the co-inventor of BiTE technology who has led its development for over 22 years from first demonstration in 1994 through multiple FDA approvals. As VP of BiTE Technology at Amgen Research Munich, he directs ongoing platform optimization and next-generation BiTE development. He received the 2023 George B. Rathmann Award for Scientific Excellence, becoming only the fourth recipient. With 137 publications and 9,932 citations, Kufer represents the continuity of BiTE innovation from Micromet through the Amgen era, ensuring the platform continues evolving to address emerging clinical needs.

Peter Kufer博士是BiTE技术的共同发明者,22年来一直领导其从1994年首次展示到多个FDA批准的开发。作为安进慕尼黑研究中心BiTE技术副总裁,他指导平台优化和下一代BiTE开发。他获得2023年George B. Rathmann科学卓越奖,成为第四位获奖者。凭借137篇出版物和9,932次引用,Kufer代表了BiTE创新从Micromet到安进时代的连续性,确保平台继续发展以应对新兴临床需求。

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🧪Research Fields 研究领域

BiTE TechnologyBiTE技术
Antibody Engineering抗体工程
Cancer Immunotherapy癌症免疫治疗
T-cell RedirectionT细胞重定向

🎓Key Contributions 主要贡献

BiTE Technology Co-invention

Co-invented BiTE platform with first demonstration of T-cell redirection via bispecific antibodies in 1994

Platform Leadership

22+ years of continuous BiTE platform development from Micromet founding through Amgen acquisition and beyond

Representative Works 代表性著作

[1]

T cell-engaging BiTE antibodies - Mechanism of action and implications for development

Immunological Reviews (2016)

Comprehensive platform review from technology inventor perspective

[2]

CD33/CD3 bispecific antibody (AMG 330) demonstrates prolonged pharmacokinetics

Clinical Cancer Research (2019)

Next-generation BiTE optimization for AML

🏆Awards & Recognition 奖项与荣誉

🏆George B. Rathmann Award for Scientific Excellence (2023)
🏆BiTE technology first presented at scientific meeting (1994)

📄Data Sources 数据来源

Last updated: 2026-03-11 | All information from publicly available academic sources

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