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clinical / clinicalPancreatic Cancer

Pascal Hammel

帕斯卡尔·阿梅尔

MD, PhD

🏢Beaujon Hospital / Paris Cité University (AP-HP)(博容医院/巴黎城市大学(公共援助医院))🌐France

Professor of Gastroenterology and Digestive Oncology胃肠病学与消化肿瘤学教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Prof. Pascal Hammel is a leading French gastroenterologist and oncologist specializing in pancreatic cancer at Beaujon Hospital. He led the pivotal LAP07 phase III trial on chemoradiation in locally advanced PDAC and has contributed extensively to understanding IPMN natural history and pancreatic cyst surveillance.

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🧪Research Fields 研究领域

Pancreatic Cancer胰腺癌
Chemoradiation放化疗
LAP07 TrialLAP07试验
Locally Advanced PDAC局部晚期胰腺癌
Pancreatic Cysts胰腺囊肿

🎓Key Contributions 主要贡献

Chemoradiation in Locally Advanced PDAC

Led the LAP07 international phase III trial that showed chemoradiation after induction chemotherapy does not improve overall survival in locally advanced PDAC, definitively shaping guidelines against routine upfront CRT.

Pancreatic Cyst Surveillance

Made landmark contributions to IPMN natural history studies and international consensus guidelines on pancreatic cyst surveillance, reducing unnecessary surgery while identifying high-risk lesions.

Representative Works 代表性著作

[1]

LAP07: effect of chemoradiotherapy vs chemotherapy on disease control in locally advanced pancreatic cancer

JAMA (2016)

Landmark trial showing CRT after gemcitabine induction did not improve OS versus continued chemotherapy in LAPC.

[2]

International consensus guidelines on pancreatic cyst management: Fukuoka revision

Pancreatology (2023)

Co-authored updated consensus on risk stratification and surveillance intervals for pancreatic cystic neoplasms.

🏆Awards & Recognition 奖项与荣誉

🏆French National Academy of Medicine Prize
🏆ESMO GI Oncology Research Award
🏆Société Nationale Française de Gastro-Entérologie Lifetime Achievement Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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