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Immunotherapy / 免疫治疗Bispecific AntibodiesBispecific T-cell Engager Pioneer

Noopur Raje

努普尔·拉杰

M.D.

🏢Massachusetts General Hospital / Harvard Medical School(麻省总医院/哈佛医学院)🌐USA

Director, Center for Multiple Myeloma; Rita M. Kelley Chair in Oncology多发性骨髓瘤中心主任;Rita M. Kelley肿瘤学讲席教授

2
Key Papers
4
Awards
2
Key Contributions

👥Biography 个人简介

Noopur Raje is a translational researcher who uniquely bridges T-cell immunotherapy and myeloma bone biology. As Director of the Center for Multiple Myeloma at Massachusetts General Hospital and Rita M. Kelley Chair in Oncology, she has built one of America's leading academic myeloma programs since 2005. Her participation in MagnetisMM trials contributed to FDA approval of elranatamab (2023), while her laboratory research on RANK/RANKL signaling led to denosumab approval for myeloma bone disease. She serves as Secretary of the International Myeloma Society. With 744 publications and 51,763 citations (D-index 107), Raje ranks among the world's most influential myeloma researchers.

Noopur Raje博士是一位独特地连接T细胞免疫治疗和骨髓瘤骨生物学的转化研究者。作为麻省总医院多发性骨髓瘤中心主任和Rita M. Kelley肿瘤学讲席教授,自2005年以来她建立了美国领先的学术骨髓瘤项目之一。她参与MagnetisMM试验促成了elranatamab的FDA批准(2023年),同时她关于RANK/RANKL信号通路的实验室研究促成了denosumab用于骨髓瘤骨病的批准。她担任国际骨髓瘤学会秘书长。凭借744篇出版物和51,763次引用(D指数107),Raje位列全球最具影响力的骨髓瘤研究者之列。

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🧪Research Fields 研究领域

BCMA Bispecific AntibodiesBCMA双特异性抗体
ElranatamabElranatamab
Bone Biology骨生物学
Translational Research转化研究

🎓Key Contributions 主要贡献

Elranatamab Development

Key investigator in MagnetisMM trials leading to second BCMA bispecific FDA approval

Bone Biology Translation

Laboratory research on RANK/RANKL contributed to denosumab approval for myeloma

Representative Works 代表性著作

[1]

Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial

Nature Medicine (2023)

MagnetisMM-1 phase 1 results

[2]

Bone Disease in Multiple Myeloma: Biologic and Clinical Implications

Cells (2022)

Comprehensive bone biology review

🏆Awards & Recognition 奖项与荣誉

🏆Rita M. Kelley Chair in Oncology (2013)
🏆LLS Clinical Scholar Award (2017)
🏆Secretary, International Myeloma Society
🏆D-index 107

📄Data Sources 数据来源

Last updated: 2026-03-11 | All information from publicly available academic sources

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