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clinical / clinicalpediatric osteosarcoma and Ewing sarcoma

Neyssa Marina

内萨·马里纳

MD

🏢Stanford University School of Medicine(斯坦福大学医学院)🌐USA

Professor of Pediatric Oncology儿科肿瘤学教授

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Key Contributions

👥Biography 个人简介

Neyssa Marina is a pediatric oncologist who has dedicated her career to clinical research in osteosarcoma and Ewing sarcoma through leadership in Children Oncology Group trials. She contributed to defining the MAP (methotrexate, doxorubicin, cisplatin) chemotherapy backbone for osteosarcoma through AOST0331 and related studies, and has investigated addition of novel agents to this backbone. Marina has also led long-term follow-up studies of pediatric bone tumor survivors, characterizing cardiac, auditory, and secondary cancer late effects. Her advocacy for inclusion of rare tumor histotypes in COG trials has advanced evidence generation in underfunded pediatric sarcomas.

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🧪Research Fields 研究领域

osteosarcoma骨肉瘤
Ewing sarcoma尤文肉瘤
MAP chemotherapyMAP化疗方案
COG sarcoma trialsCOG肉瘤试验
late effects pediatric bone tumors儿科骨肿瘤晚期效应

🎓Key Contributions 主要贡献

COG Osteosarcoma Trial Leadership

Led and contributed to multiple COG osteosarcoma trials establishing the MAP chemotherapy backbone and investigating augmented regimens, generating pivotal evidence in this rare pediatric cancer.

Pediatric Sarcoma Survivorship

Led systematic late effects assessment in pediatric bone tumor survivors including cardiac and renal toxicity surveillance, contributing to COG survivorship guidelines for osteosarcoma and Ewing sarcoma.

Representative Works 代表性著作

[1]

Results of Children Oncology Group AOST0331 Study: A Phase III Trial for Osteosarcoma

Journal of Clinical Oncology (2015)

COG phase III osteosarcoma trial outcomes with MAP backbone.

[2]

Comparison of Glomerular Filtration Rate in Childhood Cancer Survivors with and Without Cisplatin Exposure

Pediatric Blood and Cancer (2010)

Late effects of cisplatin on renal function in pediatric sarcoma survivors.

🏆Awards & Recognition 奖项与荣誉

🏆Children Oncology Group Distinguished Service Award
🏆ASCO Young Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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