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clinical / clinicalBreast Cancer

Nadia Harbeck

纳迪娅·哈贝克

MD

🏢LMU University Hospital Munich; Breast Center(慕尼黑路德维希马克西米利安大学医院乳腺中心)🌐Germany

Professor of Gynecology and Obstetrics; Head, Breast Center妇产科学教授;乳腺中心主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Internationally recognized leader in early breast cancer treatment optimization at LMU Munich, directing the ADAPT umbrella trial program that uses early response to guide adaptive neoadjuvant therapy across breast cancer subtypes, advancing response-guided strategies.

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🧪Research Fields 研究领域

Breast Cancer乳腺癌
Early Breast Cancer早期乳腺癌
Neoadjuvant Therapy新辅助治疗
ADAPT TrialADAPT试验
CDK4/6 InhibitorsCDK4/6抑制剂

🎓Key Contributions 主要贡献

Adaptive Neoadjuvant Breast Cancer Therapy

Designed and led the ADAPT umbrella trial platform enabling response-guided de-escalation and escalation of neoadjuvant therapy in early breast cancer, establishing early endocrine sensitivity and Ki-67 response as actionable biomarkers.

Representative Works 代表性著作

[1]

Neoadjuvant Chemotherapy and HER2 Blockade for HER2-Positive Early Breast Cancer: The WSG ADAPT HER2+/HR- Phase II Trial

Journal of Clinical Oncology (2022)

ADAPT HER2+ trial demonstrating trastuzumab plus pertuzumab without chemotherapy achieves high pCR in selected HER2+/HR- early breast cancer patients.

🏆Awards & Recognition 奖项与荣誉

🏆AGO Breast Cancer Award
🏆DGGG Research Prize
🏆ESMO Breast Cancer Guidelines Chair

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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