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head-neck-oncology / head-neck-oncologyHPV-related cancer

Maura L. Gillison

莫拉·吉利森

MD, PhD

🏢MD Anderson Cancer Center(德克萨斯大学MD安德森癌症中心)🌐USA

Professor, Department of Thoracic/Head and Neck Medical Oncology胸部/头颈部肿瘤内科学教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Maura Gillison is the world's foremost authority on HPV-associated oropharyngeal cancer. She discovered the causal link between HPV16 and oropharyngeal squamous cell carcinoma, transforming understanding of a global epidemic. Her work underpins de-escalation strategies and HPV-specific clinical trials.

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🧪Research Fields 研究领域

HPV-Related Oropharyngeal CancerHPV相关口咽癌
Head and Neck Epidemiology头颈部肿瘤流行病学
HNSCC头颈鳞状细胞癌
Viral Oncology病毒肿瘤学

🎓Key Contributions 主要贡献

HPV Oncogenesis Discovery

First demonstrated HPV16 as an etiologic cause of oropharyngeal squamous cell carcinoma, fundamentally redefining head and neck cancer biology and epidemiology.

De-escalation Trials

Led ECOG-ACRIN E1308 and other pivotal trials exploring treatment de-escalation for HPV-positive oropharyngeal cancer to reduce long-term toxicity.

Representative Works 代表性著作

[1]

Evidence for a Causal Association between Human Papillomavirus and a Subset of Head and Neck Cancers

Journal of the National Cancer Institute (2000)

Seminal paper establishing HPV16 as a cause of oropharyngeal SCC, launching a new era of head and neck cancer research.

[2]

Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab for HPV-Associated Resectable Oropharyngeal Squamous Cell Carcinoma

Journal of Clinical Oncology (2015)

ECOG-ACRIN E1308 demonstrating feasibility of de-escalation in favorable HPV+ oropharyngeal cancer.

🏆Awards & Recognition 奖项与荣誉

🏆NCI Outstanding Investigator Award
🏆AACR Award for Outstanding Achievement in Cancer Research
🏆Howard Hughes Medical Institute Investigator

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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