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targeted-therapy / targeted-therapyLymphoma

Martin Dreyling

马丁·德雷林

MD, PhD

🏢LMU University Hospital Munich(慕尼黑大学医院)🌐Germany

Professor of Medicine; Head, Lymphoma Section医学教授;淋巴瘤科主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Prof. Martin Dreyling is one of Europe's foremost authorities on mantle cell lymphoma (MCL). He led the landmark TRIANGLE trial, which redefined frontline MCL treatment by incorporating ibrutinib into induction and maintenance, challenging the established role of autologous stem cell transplantation.

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🧪Research Fields 研究领域

Mantle Cell Lymphoma套细胞淋巴瘤
BTK InhibitorsBTK抑制剂
TRIANGLE TrialTRIANGLE试验
Indolent Lymphomas惰性淋巴瘤

🎓Key Contributions 主要贡献

TRIANGLE Trial — Redefining MCL Frontline Therapy

Led the TRIANGLE trial demonstrating that ibrutinib added to frontline R-CHOP/R-DHAP and maintenance significantly improved outcomes in MCL, questioning the necessity of autologous SCT in the BTK inhibitor era.

Representative Works 代表性著作

[1]

Ibrutinib Combined with Immunochemotherapy with or without Autologous Stem-Cell Transplantation in Previously Untreated Patients with Mantle Cell Lymphoma (TRIANGLE)

The Lancet (2024)

Randomized trial showing ibrutinib-containing regimens superior to standard immunochemotherapy+ASCT in frontline MCL, reshaping treatment guidelines.

🏆Awards & Recognition 奖项与荣誉

🏆European Hematology Association Award for Excellence
🏆German Society of Hematology and Oncology Outstanding Research Prize

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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