Markus Möhler
马库斯·默勒
MD, PhD
Professor of Medicine, Director of GI Oncology医学教授，胃肠肿瘤科主任
👥Biography 个人简介
Prominent German GI oncologist who co-designed and led the FLOT4-AIO trial transforming perioperative gastric cancer treatment. Principal investigator of RAMSES and other biomarker-driven trials. Leads the AIO gastric cancer working group and shapes European gastric cancer treatment guidelines.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
FLOT Perioperative Regimen
Co-designed the FLOT4-AIO trial, demonstrating FLOT chemotherapy nearly doubles pathological complete response rate and improves survival over ECF perioperatively.
RAMSES Trial and Ramucirumab
Led RAMSES trial evaluating ramucirumab with FOLFOX as perioperative therapy, advancing antiangiogenic strategies in resectable gastric cancer.
Representative Works 代表性著作
FLOT4-AIO: Perioperative FLOT versus ECF/ECX for resectable gastric or GEJ adenocarcinoma
The Lancet (2019)
Definitive trial replacing ECF with FLOT as perioperative chemotherapy standard for gastric cancer.
RAMSES/FLOT7: Ramucirumab plus FLOT as perioperative chemotherapy in patients with resectable gastric or GEJ adenocarcinoma
ESMO Open (2022)
Explored ramucirumab addition to FLOT in perioperative setting for gastric cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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