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clinical / clinicalBiliary Tract & Cholangiocarcinoma

Markus Moehler

马库斯·默勒

MD, PhD

🏢University Medical Center Mainz (Johannes Gutenberg University)(美因茨大学医学中心(约翰内斯·古腾堡大学))🌐Germany

Professor and Head, Department of Internal Medicine I (GI Oncology)内科I科(消化肿瘤)系主任及教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Markus Moehler, MD, PhD is Professor and Head of GI Oncology at University Medical Center Mainz and a key European clinical trialist across gastrointestinal and biliary tract cancers. He has contributed to major phase III immunotherapy trials in GI oncology including CheckMate 649, and has established Mainz as a leading center for biliary tract cancer clinical research in Germany.

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🧪Research Fields 研究领域

Gastrointestinal Cancers消化道肿瘤
Biliary Tract Cancer胆道肿瘤
Gastric Cancer胃癌
Immunotherapy免疫治疗
Nivolumab纳武利尤单抗
Multimodal Oncology综合肿瘤治疗

🎓Key Contributions 主要贡献

Immunotherapy in GI and Biliary Tract Cancers

Led and contributed to multiple phase III trials of PD-1/PD-L1 inhibitors in gastric, gastroesophageal, and biliary tract cancers, advancing immunotherapy as a therapeutic cornerstone across GI malignancies.

European Biliary Tract Cancer Clinical Research

Established and directed clinical trial infrastructure at Mainz for biliary tract cancer studies, enrolling patients in key international trials and contributing to European GI oncology consortium efforts.

Representative Works 代表性著作

[1]

Nivolumab plus chemotherapy versus chemotherapy as first-line treatment for advanced gastric cancer/GEJ cancer (CheckMate 649)

The Lancet (2021)

Phase III trial establishing nivolumab plus chemotherapy as a new first-line standard in advanced gastric/GEJ cancer, with Moehler as a key contributing investigator.

🏆Awards & Recognition 奖项与荣誉

🏆DGHO (German Society of Hematology and Oncology) Excellence Award
🏆ESMO Faculty Recognition Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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