Marc Sanson
马克·桑森
MD, PhD
Professor of Neuro-Oncology; Head, Neuro-Oncology Department神经肿瘤科主任、教授
👥Biography 个人简介
Marc Sanson is France's leading neuro-oncologist and a pioneer in glioma molecular biology. His research on IDH mutations, 1p/19q co-deletion, and TERT promoter mutations has fundamentally shaped the WHO 2021 classification of diffuse gliomas and informed targeted therapy development.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
IDH Mutations in Glioma
Characterized IDH1/2 mutation frequency and functional consequences across glioma subtypes, establishing it as a primary classification marker.
Glioma Molecular Classification
Contributed foundational data to WHO 2016 and 2021 CNS tumor classifications, integrating molecular markers with histology.
TERT Promoter Mutations
Identified TERT promoter mutation as a key co-occurring alteration with IDH wild-type GBM, improving diagnostic precision.
Representative Works 代表性著作
IDH1 and IDH2 mutations in gliomas
New England Journal of Medicine (2009)
Seminal study establishing IDH mutation prevalence and prognostic significance across diffuse glioma subtypes.
TERT promoter mutations in glioma: frequency, prognosis, and hTERT expression
Neuro-Oncology (2014)
Demonstrated TERT promoter mutations define aggressive GBM subtype and correlate with poor prognosis.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Timothy Cloughesy
UCLA Health / David Geffen School of Medicine
Patrick Y. Wen
Dana-Farber Cancer Institute / Harvard Medical School
Michael Weller
University Hospital Zurich / University of Zurich
Susan M. Chang
University of California San Francisco (UCSF)
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