Mansoor Raza Mirza
曼苏尔·拉扎·米尔扎
MD
Chief Oncologist, Department of Oncology肿瘤科主任肿瘤学家
👥Biography 个人简介
Chief Oncologist at Rigshospitalet Copenhagen and ENGOT/GCIG steering committee leader. Principal investigator of the landmark ENGOT-OV16/NOVA trial establishing niraparib maintenance, and major contributor to bevacizumab and PARP inhibitor trials across Europe.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Niraparib NOVA Trial
Led the ENGOT-OV16/NOVA trial demonstrating niraparib maintenance significantly prolonged PFS in platinum-sensitive recurrent ovarian cancer regardless of BRCA status.
ENGOT Leadership
As ENGOT steering committee member, coordinated European gynecologic oncology cooperative group trials across 15+ countries, accelerating drug development.
Bevacizumab in Ovarian Cancer
Contributed to international bevacizumab trials defining its role as maintenance and combination therapy in newly diagnosed and recurrent ovarian cancer.
Representative Works 代表性著作
Niraparib maintenance therapy in platinum-sensitive recurrent ovarian cancer (ENGOT-OV16/NOVA)
New England Journal of Medicine (2016)
Landmark trial establishing niraparib as first PARP inhibitor with benefit beyond BRCA mutation, transforming maintenance therapy in ovarian cancer.
Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer
The Lancet Oncology (2016)
Demonstrated improved PFS with VEGFR and PARP dual inhibition, supporting combination anti-angiogenic and DNA-repair strategies.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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