Shannon Neville Westin
香农·韦斯廷
MD, MPH, FACOG
Professor and Deputy Chair, Department of Gynecologic Oncology and Reproductive Medicine妇科肿瘤与生殖医学系教授兼副主任
👥Biography 个人简介
Dr. Shannon Westin at MD Anderson specializes in endometrial cancer and molecular-targeted therapies. She leads translational research programs focusing on mismatch repair deficiency, PI3K pathway inhibitors, and immunotherapy combinations in endometrial and other gynecologic malignancies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Endometrial Cancer Molecular Therapeutics
Pioneered clinical trials evaluating PI3K/AKT/mTOR pathway inhibitors in endometrial cancer, translating molecular biomarkers into targeted treatment strategies.
Mismatch Repair Research
Led studies characterizing the clinical significance of mismatch repair deficiency in endometrial cancer, informing immunotherapy patient selection and treatment algorithms.
Representative Works 代表性著作
Molecular Classification of Endometrial Cancer and Immunotherapy Response
Journal of Clinical Oncology (2021)
Demonstrated molecular subtyping of endometrial cancer predicts response to checkpoint inhibitor immunotherapy.
Selinexor in Endometrial Cancer
Journal of Clinical Oncology (2022)
Established activity of selinexor (XPO1 inhibitor) in advanced p53-mutated endometrial cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Vicky Makker
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