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clinical / clinicalEndometrial Cancer

Mansoor Raza Mirza

曼苏尔·米尔扎

MD

🏢Rigshospitalet Copenhagen University Hospital(哥本哈根大学医院(国家医院))🌐Denmark

Chief Oncologist, Department of Oncology; Chair, Nordic Society of Gynaecological Oncology (NSGO)肿瘤科首席肿瘤学家;北欧妇科肿瘤学会主席

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Mansoor Raza Mirza, MD is chief oncologist at Rigshospitalet Copenhagen and chair of NSGO, globally recognized for co-leading the RUBY trial that established dostarlimab plus carboplatin/paclitaxel as a first-line standard in dMMR/MSI-H advanced endometrial cancer.

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🧪Research Fields 研究领域

Endometrial Cancer子宫内膜癌
Dostarlimab Immunotherapydostarlimab免疫治疗
RUBY TrialRUBY试验
Gynecologic Oncology Clinical Trials妇科肿瘤临床试验
Nordic GYN Oncology北欧妇科肿瘤学

🎓Key Contributions 主要贡献

RUBY Trial: Dostarlimab in Advanced Endometrial Cancer

Co-led the RUBY phase III trial demonstrating dostarlimab plus chemotherapy significantly improved PFS and OS in dMMR/MSI-H advanced endometrial cancer, leading to regulatory approval globally.

Nordic Gynecologic Oncology Collaborative Research

Established the NSGO as a leading international platform for gynecologic oncology trials, expanding access to innovative therapies across Scandinavian and European centers.

Representative Works 代表性著作

[1]

Dostarlimab plus carboplatin-paclitaxel for advanced or recurrent endometrial cancer (RUBY)

New England Journal of Medicine (2023)

Phase III RUBY trial showing dostarlimab plus chemotherapy significantly prolonged PFS in dMMR/MSI-H advanced endometrial cancer, establishing a new standard of care.

[2]

Niraparib maintenance therapy in advanced ovarian cancer after platinum-based chemotherapy (ENGOT-OV16/NOVA)

New England Journal of Medicine (2016)

Landmark phase III trial establishing niraparib as a maintenance option for recurrent ovarian cancer, influencing gynecologic oncology practice globally.

🏆Awards & Recognition 奖项与荣誉

🏆ESGO Lifetime Achievement Award
🏆NSGO Excellence in Research Award
🏆Danish Medical Association Research Prize

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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