Laura Esserman
劳拉·埃瑟曼
MD, MBA
Director, UCSF Breast Care Center; Professor of Surgery and RadiologyUCSF乳腺护理中心主任；外科与放射学教授
👥Biography 个人简介
Laura Esserman is a visionary breast surgical oncologist and researcher championing de-escalation of surgery and personalized screening. She leads the WISDOM Study, a landmark adaptive trial comparing annual vs. personalized mammography screening, and has advanced neoadjuvant treatment paradigms.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
De-escalation of Breast Surgery
Pioneered the concept of rational surgical de-escalation, advocating for tailored surgery based on tumor biology rather than reflexive extensive resection.
WISDOM Trial
Leads the WISDOM Study, the largest US adaptive trial comparing risk-based vs. annual screening, aiming to optimize mammography with genomic and clinical risk stratification.
I-SPY Neoadjuvant Platform
Co-leads the I-SPY clinical trial network, an adaptive platform accelerating identification of effective neoadjuvant regimens and informing surgical planning.
Representative Works 代表性著作
Addressing Overdiagnosis and Overtreatment in Cancer: A Prescription for Change
The Lancet Oncology (2014)
Influential framework for reclassifying low-risk lesions and avoiding overtreatment in breast and other cancers.
The WISDOM Study: breaking the deadlock in the breast cancer screening debate
npj Breast Cancer (2017)
Presented the design of the WISDOM adaptive personalized screening trial, reshaping screening research.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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