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clinical / clinicalProstate Cancer

Kim N. Chi

金·池

MD, FRCPC

🏢BC Cancer, University of British Columbia(不列颠哥伦比亚癌症中心,不列颠哥伦比亚大学)🌐Canada

Professor of Medicine; Vice President, Research, BC Cancer医学教授;不列颠哥伦比亚癌症中心研究副总裁

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Kim Chi is a leading Canadian prostate cancer clinician-scientist at BC Cancer. He led the PROfound trial establishing olaparib for BRCA1/2- and HRR-mutated mCRPC, and has contributed extensively to biomarker-driven therapy and androgen receptor pathway targeting in advanced prostate cancer.

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🧪Research Fields 研究领域

Prostate Cancer前列腺癌
PARP InhibitorsPARP抑制剂
BRCA MutationsBRCA突变
PROfound TrialPROfound试验
mCRPC转移性去势抵抗性前列腺癌

🎓Key Contributions 主要贡献

PARP Inhibition in HRR-Mutated mCRPC

Led the PROfound phase III trial showing olaparib improved radiographic progression-free survival in mCRPC patients with homologous recombination repair gene alterations, leading to FDA approval.

Representative Works 代表性著作

[1]

Olaparib for Metastatic Castration-Resistant Prostate Cancer (PROfound)

New England Journal of Medicine (2020)

Landmark trial demonstrating olaparib's efficacy in BRCA1/2- or ATM-mutated mCRPC, establishing precision oncology in prostate cancer.

🏆Awards & Recognition 奖项与荣誉

🏆Canadian Cancer Society Research Institute Award
🏆ASCO Genitourinary Cancers Symposium Outstanding Investigator

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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