Jochen H. Lorch
约亨·洛赫
MD, MS
Professor of Medicine; Director, Head and Neck Oncology Program医学教授；头颈部肿瘤项目主任
👥Biography 个人简介
Dr. Jochen Lorch is an internationally recognized specialist in anaplastic and rare thyroid cancers. Formerly at Dana-Farber Cancer Institute, he has led clinical trials in BRAF-combination and immunotherapy approaches for anaplastic thyroid carcinoma, one of the deadliest human malignancies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Anaplastic Thyroid Cancer Management
Established multidisciplinary treatment protocols for anaplastic thyroid carcinoma combining BRAF/MEK inhibition, immunotherapy, and radiation, significantly improving outcomes in this historically rapidly fatal disease.
Rare Thyroid Tumor Clinical Research
Led investigator-initiated and cooperative group trials for rare thyroid malignancies including Hurthle cell carcinoma and poorly differentiated thyroid cancer, defining systemic therapy strategies where evidence was previously lacking.
Representative Works 代表性著作
Antitumor activity of pembrolizumab in thyroid cancer: preliminary results from the phase Ib KEYNOTE-028 study
Journal of Clinical Oncology (2017)
Early clinical data demonstrating pembrolizumab activity in advanced thyroid cancers, providing rationale for further immunotherapy investigation in this indication.
Multimodal treatment of anaplastic thyroid carcinoma with BRAF inhibition, immunotherapy, and radiation
Thyroid (2021)
Clinical series demonstrating prolonged survival with combined BRAF-targeted therapy, immune checkpoint blockade, and radiotherapy in ATC patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Hope S. Rugo
University of California, San Francisco (UCSF)
Maryam B. Lustberg
Yale School of Medicine / Yale Cancer Center
Sara M. Tolaney
Dana-Farber Cancer Institute / Harvard Medical School
Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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