Jennifer S. Temel
詹妮弗·特梅尔
MD
Director, Cancer Outcomes Research; Professor of Medicine癌症结局研究主任;医学教授
👥Biography 个人简介
Jennifer S. Temel, MD is Director of Cancer Outcomes Research at Massachusetts General Hospital and Professor of Medicine at Harvard Medical School. She is best known for her landmark 2010 New England Journal of Medicine study demonstrating that early palliative care integration in patients with metastatic non-small cell lung cancer not only improved quality of life and mood, but was associated with longer survival compared to standard oncologic care alone. This randomized controlled trial fundamentally shifted how the oncology community approaches palliative care — moving it from end-of-life practice to a concurrent therapeutic partner. Dr. Temel has continued to expand this paradigm, leading trials of early palliative care in other advanced cancer populations and investigating patient-reported outcomes, goals of care conversations, and health care utilization at the end of life. She has authored over 180 peer-reviewed publications and serves on national guidelines committees for palliative care integration in oncology.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Early Palliative Care Integration in Metastatic NSCLC
Led the landmark NEJM 2010 randomized trial showing early palliative care concurrent with standard oncology care improved quality of life, reduced aggressive end-of-life interventions, and was associated with a median survival benefit of approximately 2.7 months in metastatic NSCLC, transforming oncology practice guidelines globally.
Expansion of Early Palliative Care to Other Cancers
Extended the early palliative care model to gastrointestinal cancers and hematologic malignancies through subsequent randomized trials, establishing the generalizability of concurrent palliative care across diverse oncology settings.
Patient-Reported Outcomes and Goals of Care
Developed and validated patient-reported outcome frameworks for assessing quality of life, symptom burden, and alignment of care with patient preferences in advanced cancer, informing clinical practice and regulatory endpoints.
Representative Works 代表性著作
Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
New England Journal of Medicine (2010)
Landmark randomized trial demonstrating early integrated palliative care improved quality of life, reduced depressive symptoms, decreased aggressive end-of-life care, and was associated with longer survival in metastatic NSCLC.
Randomized Trial of Early Integrated Palliative and Oncologic Care
JAMA Oncology (2017)
Multi-site trial extending early palliative care benefit to patients with advanced GI cancers, confirming quality-of-life improvements and enhanced patient-reported outcomes.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-20 | All information from publicly available academic sources
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