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clinical / clinicalesophageal cancer radiation oncology

Karyn A. Goodman

卡伦·古德曼

MD

🏢Icahn School of Medicine at Mount Sinai(西奈山伊坎医学院)🌐USA

Professor and Chair, Radiation Oncology放射肿瘤学系主任及教授

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Key Papers
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Key Contributions

👥Biography 个人简介

Karyn Goodman is a radiation oncologist specializing in esophageal and gastric cancer who has led trials evaluating PET-adapted radiotherapy dose escalation and novel radiation approaches in upper GI cancers. She contributed to RTOG trials evaluating chemoradiation for esophageal cancer and has investigated proton therapy to reduce treatment toxicity in thoracic irradiation. Goodman chairs the Gastrointestinal Oncology Scientific Committee for ASTRO and contributes to multidisciplinary esophageal cancer guideline development. Her translational research investigates imaging biomarkers of radiation response and normal tissue toxicity prediction.

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🧪Research Fields 研究领域

esophageal cancer radiation食管癌放射治疗
CROSS chemoradiationCROSS同步放化疗
PET-adapted radiotherapyPET适应性放疗
proton therapy esophageal质子治疗食管癌
radiation dose escalation GEJGEJ放射剂量递增

🎓Key Contributions 主要贡献

PET-Adapted Esophageal Radiotherapy

Led trials evaluating PET response-adapted radiation dose escalation in esophageal cancer, investigating whether FDG-PET response can guide individualized treatment intensification to improve outcomes.

Proton Therapy in Upper GI Cancer

Contributed to evaluation of proton therapy for esophageal and gastric cancer radiation, demonstrating reduced cardiopulmonary dose with proton beams and potential long-term toxicity advantages.

Representative Works 代表性著作

[1]

PET/CT-Guided Dose Escalation in Esophageal Cancer

International Journal of Radiation Oncology Biology Physics (2019)

PET-adapted dose escalation study in esophageal cancer.

[2]

Proton Beam Radiotherapy for Esophageal Cancer

Annals of Oncology (2022)

Proton therapy dosimetric and clinical outcomes in esophageal cancer.

🏆Awards & Recognition 奖项与荣誉

🏆ASTRO Rod Withers Distinguished Career Award
🏆ASCO GI Cancer Radiation Excellence Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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