Isabelle Ray-Coquard
伊莎贝尔·雷-科夸尔
MD, PhD
Professor of Medical Oncology; Head, Gynecologic Oncology Unit肿瘤内科学教授，妇科肿瘤部主任
👥Biography 个人简介
Isabelle Ray-Coquard is one of Europe's leading gynecologic oncologists at Centre Léon Bérard, Lyon. She is internationally recognized for her research on rare gynecologic tumors, ovarian cancer immunotherapy, and pivotal phase III trial leadership through GINECO and ENGOT networks.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Ovarian Cancer Immunotherapy
Led PAOLA-1 trial combining olaparib with bevacizumab as maintenance in advanced ovarian cancer, establishing a new first-line standard and demonstrating synergy between PARP inhibition and antiangiogenic therapy.
Rare Gynecologic Tumor Research
Founded and led international collaborations studying rare gynecologic malignancies including granulosa cell tumors and uterine sarcomas, advancing evidence-based management of understudied tumors.
Representative Works 代表性著作
Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer (PAOLA-1)
New England Journal of Medicine (2019)
Practice-changing phase III trial demonstrating olaparib plus bevacizumab maintenance significantly improves progression-free survival in advanced ovarian cancer.
Trabectedin plus PLD versus PLD in Relapsed Ovarian Cancer: INOVATYON Trial
Annals of Oncology (2020)
Phase III trial evaluating combination chemotherapy in platinum-sensitive relapsed ovarian cancer through European collaborative network.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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