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breast-oncology / breast-oncologyHER2-Low Breast Cancer

Ingrid Mayer

英格丽德·迈尔

MD, MSCI

🏢Vanderbilt-Ingram Cancer Center(范德堡大学英格拉姆癌症中心)🌐USA

Professor of Medicine, Director of Breast Cancer Research医学教授,乳腺癌研究主任

50
h-index
2
Key Papers
3
Awards
2
Key Contributions

👥Biography 个人简介

Ingrid Mayer is a leading breast oncologist at Vanderbilt, with expertise in HER2-low disease, CDK4/6 inhibitor combinations with endocrine therapy, and early-stage breast cancer clinical trials. She has shaped treatment standards across HR+, HER2-low, and luminal subtypes.

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🧪Research Fields 研究领域

Breast Oncology乳腺肿瘤学
HER2-LowHER2低表达
CDK4/6 InhibitorsCDK4/6抑制剂
Endocrine Therapy内分泌治疗

🎓Key Contributions 主要贡献

HER2-Low Breast Cancer Characterization and Treatment

Contributed to defining HER2-low as a clinically distinct entity and investigating targeted therapies including T-DXd and novel ADCs in this population.

CDK4/6 Inhibitors with Endocrine Therapy

Led trials integrating CDK4/6 inhibitors into early and metastatic HR+ breast cancer regimens, optimizing sequence and combination strategies.

Representative Works 代表性著作

[1]

Trastuzumab deruxtecan in HER2-low breast cancer: clinical and translational insights

Journal of Clinical Oncology (2023)

Provided key analyses of T-DXd activity in HER2-low disease, characterizing predictive biomarkers and informing patient selection.

[2]

Phase II study of neoadjuvant CDK4/6 inhibitor plus letrozole in early HR+ breast cancer

Annals of Oncology (2020)

Demonstrated biological activity of CDK4/6 inhibition with endocrine therapy in early-stage HR+ breast cancer neoadjuvant setting.

🏆Awards & Recognition 奖项与荣誉

🏆Vanderbilt Faculty Research Award
🏆Breast Cancer Research Foundation Investigator Award
🏆Susan G. Komen Scholar Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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